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    • RPL Community Registry
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Recurrent Pregnancy Loss Association

Recurrent Pregnancy Loss Association Awareness. Advocacy. Answers.

Recurrent Pregnancy Loss Association Awareness. Advocacy. Answers. Recurrent Pregnancy Loss Association Awareness. Advocacy. Answers. Recurrent Pregnancy Loss Association Awareness. Advocacy. Answers.

Patients Hold the Power

As individuals and couples who have experienced recurrent pregnancy loss, we have the ability to help doctors and scientists understand early pregnancy and causes of miscarriage.  By choosing to participate in research we can help change the future of care. 

RPLA Studies

RPL Community Registry

Goal: The RPL Community Registry aims to support RPL research by:  

  • Providing anonymized data for doctors and scientists conducting research into the causes of, and treatments for, recurrent miscarriage 
  • Connecting interested patients with relevant research studies, while protecting their privacy
  • Educating families, healthcare providers, and others about RPL 

What's Involved: Answering health surveys online

Location: You can join the RPL Community Registry from any location, US and International.  However, currently all surveys are in English.    

Eligibility: The RPL Community Registry is open to any individual, 18 years of age or older, who self reports having experienced two or more pregnancy losses/miscarriages.  

Primary Investigator: Recurrent Pregnancy Loss Association

Contact: Please email info@rplassocation.org if you have questions. 

Join Now

Clinical Trials

ClinicalTriales.gov is a resource that provides information on publicly and privately supported clinical studies. The site is maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH).

Search Studies on RPL

Other Studies

Disclaimer:  Studies listed here are an effort to share information.  Recurrent Pregnancy Loss Association makes no guarantee about the safety or scientific validity of any opportunity list.  RPLA is not involved in these research efforts and does not benefit in any way from your participation or lack thereof.  If you have specific questions or concerns, please reach out to the respective study coordinators.

The HOPE Project

Goal: The goal of The HOPE Project (Harness multiple Opportunities for Pregnancy loss Exploration) is to find explanations of pregnancy loss and learn how we can predict future pregnancy outcomes. 

What's Involved: The HOPE Project includes multiple studies, what's involved will vary.   

Location: You can join the HOPE registry from any location, but some of the studies require travel to Stanford, University of California at San Francisco (UCSF), or Oregon Health and Science University (OHSU)

Eligibility: The first step is enrolling in the HOPE registry.  After that you will be able to learn more about specific studies that you are eligible for. 

Primary Investigator: Ruth Lathi, MD

Contact: Project email, rei-research@list.stanford.edu


Find out more

The GPRPL Study

Goal: The goal of the GPRPL Study (Genomic Predictors of Recurrent Pregnancy Loss) is to find new genetic causes for recurrent pregnancy loss. 

What's Involved: A blood sample from you and your partner, a tissue sample from your lost pregnancy, access to your medical records, and a potential clinical evaluation.   

Location: The primary research team is at Yale, participants are being recruited from multiple sites across the US, please reach out to the research contact below to determine eligibility.

Eligibility: Couples who are having (or have recently had) their second+ pregnancy loss before 20 weeks' gestation.

Primary Investigator: Yong-Hui Jiang, MD

Contact: Dr. Winifred Mak, makw@uthscsa.edu


Find out more

Genetics of Recurrent Pregnancy Loss Study

Goal: Identification of genetic causes of RPL

What's Involved: Genetic evaluation of miscarriage tissue

Location: University of Pittsburgh

Eligibility: 

  • Unexplained RPL (2 or more losses with no discernable cause)
  • Women of reproductive age up to 37
  • Currently not pregnant
  • Participation of both partners

Primary Investigator: Svetlana Yatsenko, MD

Contact: Jessica Settino, settinoj@upmc.edu or 412-641-7457 

Find out more

ALOE: Pregnancy Loss Research Study

Goal: To understand how pregnancy loss affects couples' sexuality and relationships.

What's Involved: Completion of an online survey

Eligibility: 

  • Have experienced a pregnancy loss within the past 4 months
  • Have been in a relationship with your partner for 1+ years
  • Are NOT currently receiving fertility treatment

Primary Investigators: 

  • David Allsop, Ph.D. Student (Dalhousie University)
  • Natalie Rosen, Ph.D., R. Psych. (Dalhousie University & IWK Health Centre)
  • Heather Cockwell, MD, FRCSC (Dalhousie University & IWK Health Centre)

Contact: aloe@dal.ca 

Find out more

Tommy's Miscarriage Research

We encourage those in the UK to check out Tommy's.  They conducting fantastic research and doing a lot of work to improve treatment practices. 

Find out more

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